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Dual-Effect Vacuum Concentrator for Pharma Food is an energy-efficient concentration system designed for both pharmaceutical and food industries, leveraging two consecutive evaporation stages to reduce energy consumption while maintaining product quality. Unlike single-effect concentrators, it reuses secondary steam from the first effect to heat the second effect, cutting energy usage by 30–40%—a key advantage for large-scale production. Constructed from 316L stainless steel (pharmaceutical grade) and 304 stainless steel (food grade, non-wetted parts), it complies with GMP, FDA 21 CFR Part 177, and EHEDG standards. Core parameters include a working vacuum range of -0.085 to -0.098 MPa (dual-stage adjustable), a heating temperature of 45–70°C, and a concentration ratio of 1:3 to 1:20. It is ideal for concentrating heat-sensitive materials such as pharmaceutical extracts, fruit juices, and dairy products.
• Dual-Effect Energy Saving: The two-effect design recycles secondary steam (from the first effect’s evaporation) as a heat source for the second effect, reducing steam consumption to 0.4–0.6 kg steam/kg water evaporated (vs. 1.1–1.3 kg for single-effect models).
• Dual-Stage Vacuum Control: Each effect has an independent vacuum pump (double-stage rotary vane type), allowing precise adjustment of vacuum degree (first effect: -0.06 to -0.07 MPa, second effect: -0.09 to -0.098 MPa) to match different material evaporation requirements.
• Sanitary & Versatile Design: Wetted parts feature electropolished surfaces (Ra < 0.4 μm) and seamless welding (ASME BPE standards) for easy cleaning; the system supports both batch and continuous operation, with a processing capacity of 100–2000 kg/h (water evaporation rate).
• Advanced Condensation System: A shell-and-tube condenser (heat exchange area: 3–20 m²) with a low-temperature cooling water loop (5–15°C) achieves a solvent recovery rate of >98%, minimizing environmental emissions and solvent waste.
• Material Protection Technology: The low-temperature evaporation (minimum 45°C) and gentle agitator (10–25 rpm) prevent thermal degradation of heat-sensitive components—e.g., preserving >90% of vitamin C in fruit juice and >95% of API activity in pharmaceutical extracts.
• Pharmaceutical Industry:
◦ Concentrates antibiotic solutions (e.g., erythromycin, tetracycline) at 50–60°C to avoid drug decomposition, ensuring compliance with USP <788> particulate matter standards.
◦ Processes herbal extracts (e.g., licorice, chrysanthemum) for oral solid dosage forms (tablets, capsules), maintaining the integrity of active herbal compounds.
• Food Industry:
◦ Concentrates fruit juices (orange, apple, grape) to 65–75° Brix for juice concentrates, preserving natural flavors and pigments (e.g., carotenoids in orange juice).
◦ Reduces moisture in dairy products (e.g., milk protein concentrates, whey protein) from 80% to 30% moisture content for easier drying and storage.
Q1: What is the maximum water evaporation rate of this concentrator?
A1: Standard models offer evaporation rates from 100 kg/h to 2000 kg/h; custom systems can achieve up to 3000 kg/h for large-scale food processing plants (e.g., juice concentrate factories).
Q2: Can it switch between pharmaceutical and food-grade operations?
A2: Yes. The system features a full CIP + SIP (Sterilization-in-Place) function (SIP temperature: 121°C, 30 minutes) that eliminates cross-contamination, allowing safe switching between pharmaceutical and food applications with minimal downtime.
Q3: How does it handle high-viscosity materials (e.g., honey, thick herbal extracts)?
A3: It is equipped with a variable-speed agitator (up to 50 rpm) and a jacketed heating system with adjustable temperature gradients, enabling concentration of materials with viscosities up to 10,000 cP without sticking or uneven heating.

| Volume of extract can | 1m3, 2m3,3m3,6m3 |
| Volume of concentrator | 0.5m3,1m3,1.5m3,2.5m3 |
| Temperature for water distillation | 90~100℃ |
| Temperature for alcohol distillation | 78~83℃ |
| Distillation time | 4~5H/B |
| Vacuum degree | 0.05~0.08MPa |
| Used pressure | 0.08-0.2MPa |
Project Unit | Traditional Chinese medicine dual-effect concentrating | Ordinary traditional Chinese medicine dual-effect | ||
High pressure ejection steam pressure(Mpa) | 0.5~0.6 | 0.1~0.25 | ||
Noise of hot energy compressor(DB(A)) | 80~85 | |||
Theoretical steam-water ratio(kg steam kg water) | 0.30 | 0.50 | ||
Actual steam-water ratio(kg steam kg water) | 0.33~0.35 | 0.65~0.75 | ||
The first effect | Shell side vacuum degree(MPa) | 0.040~0.030 | 0.1~0.25 | |
Heating steam temperature(℃) | 85~90 | 110~120 | ||
Evaporation chamber vacuum degree(MPa) | 0.068-0.060 | 0.040~0.030 | ||
Boiling point(℃) | 70~75 | 85~90 | ||
The second effect | Shell side vacuum degree(MPa) | 0.068-0.060 | 0.040~0.030 | |
Heating steam temperature(℃) | 70~75 | 85~90 | ||
Evaporation chamber vacuum degree(MPa) | 0.089~0.082 | 0.080~0.070 | ||
Boiling point(℃) | 52~57 | 60~67 | ||
Discharging method of condensed water in chambers of various effects | With isopiestic pressure water discharging serial self-evaporation, some heat of the condensed water can be recycled. | |||
Cooling water volume | Water inlet temperature 25℃ | The cooling water volume of the device is taken as 1. | Under same evaporation,the cooling water volume is 1.43. | |
Operability | Simple operation and adjustment and easy observation | Simple operation and adjustment and easy observation | ||
Economical efficiency | Small land area,higher equipment cost and low using cost | Small land area,lower equipment | ||
Increasing equipment investment cost | 1.50 | Taking the cost of the item as 1 | ||